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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL4
All Species:
34.24
Human Site:
T57
Identified Species:
53.81
UniProt:
Q8WUA2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WUA2
NP_624311.1
492
57225
T57
I
I
Q
T
G
D
P
T
G
T
G
R
G
G
E
Chimpanzee
Pan troglodytes
XP_527529
607
69328
T172
I
I
Q
T
G
D
P
T
G
T
G
R
G
G
E
Rhesus Macaque
Macaca mulatta
XP_001084421
492
57172
T57
I
I
Q
T
G
D
P
T
G
T
G
R
G
G
E
Dog
Lupus familis
XP_541147
492
57155
T57
I
I
Q
T
G
D
P
T
G
T
G
R
G
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXG3
492
57212
T57
I
I
Q
T
G
D
P
T
G
T
G
R
G
G
E
Rat
Rattus norvegicus
NP_001101927
357
40656
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506397
487
56623
G54
I
Q
T
G
D
P
L
G
T
G
R
G
G
E
S
Chicken
Gallus gallus
XP_419663
478
55881
M57
I
I
Q
T
G
D
P
M
G
T
G
R
G
G
E
Frog
Xenopus laevis
Q6GLX7
477
54856
T69
I
I
Q
G
G
D
P
T
G
T
G
T
G
G
E
Zebra Danio
Brachydanio rerio
NP_001121802
454
52864
T57
I
I
Q
T
G
D
P
T
G
T
G
R
G
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651291
653
75452
S57
I
A
Q
T
G
D
P
S
G
A
G
D
G
G
S
Honey Bee
Apis mellifera
XP_001121334
512
60307
T57
I
A
Q
T
G
D
P
T
G
T
G
K
G
G
E
Nematode Worm
Caenorhab. elegans
NP_492343
427
50388
F42
K
Y
Y
N
L
N
Q
F
H
S
I
E
R
N
Y
Sea Urchin
Strong. purpuratus
XP_001192414
536
61906
E55
G
D
Q
A
K
Y
F
E
M
E
N
S
P
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871A4
494
56481
L57
S
F
Q
T
G
D
P
L
G
P
L
S
S
E
S
Conservation
Percent
Protein Identity:
100
80.8
98.7
98.1
N.A.
96.7
71.9
N.A.
77
80.8
23.5
69.7
N.A.
42.4
48.6
47.5
51.1
Protein Similarity:
100
80.8
98.9
98.7
N.A.
98.1
72.3
N.A.
86.1
89
45.7
81
N.A.
55.9
65.8
65.6
65.4
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
13.3
93.3
86.6
100
N.A.
66.6
86.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
13.3
93.3
86.6
100
N.A.
73.3
93.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
0
0
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
74
0
0
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
7
0
7
0
7
0
14
60
% E
% Phe:
0
7
0
0
0
0
7
7
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
14
74
0
0
7
74
7
67
7
74
67
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
74
54
0
0
0
0
0
0
0
0
7
0
0
0
7
% I
% Lys:
7
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
0
7
0
7
7
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
7
0
0
0
0
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
7
74
0
0
7
0
0
7
0
0
% P
% Gln:
0
7
80
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
47
7
7
0
% R
% Ser:
7
0
0
0
0
0
0
7
0
7
0
14
7
0
20
% S
% Thr:
0
0
7
67
0
0
0
54
7
60
0
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
0
7
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _